Jerri Blank (Amy Sedaris) is a forty-seven year old ex-con who decides to return to her childhood home after thirty-two years working the streets and in prison. Upon her arrival, she discovers her father is in a self-induced coma. Hoping to wake him, Jerri decides to turn her life around by picking it up exactly where she left off - as a high school freshman. But for a former boozer, user, and loser, hanging with the `in-crowd is going to be harder than turning tricks!